Medications That Could Be Contributing to Your Weight Gain

25. Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs): The Double-Edged Sword of Mental Health

SNRIs, including venlafaxine and duloxetine, are a class of antidepressants that work by increasing serotonin and norepinephrine levels in the brain. While they can be highly effective for treating depression and anxiety, they can also lead to weight gain. This happens for a few reasons: an increase in appetite, a slowing of metabolism, and in some cases, a normalization of mood that leads to more regular eating patterns. It's a tricky balance. For some, weight gain is a sign that the medication is working and they're no longer suppressing their hunger. If you're concerned, talk to your doctor about exploring other medications or incorporating mindful eating and regular exercise into your daily routine.

26. Antifungals: Treating Infections with an Unforeseen Consequence

Antifungal medications, particularly oral drugs used for long-term treatment of conditions like nail fungus or systemic infections, can sometimes lead to weight gain. While not a primary side effect, some antifungals can affect liver function and alter the gut microbiome, which plays a critical role in metabolism and weight regulation. These medications may also cause fatigue, leading to a decrease in physical activity. If you are on a long-term course of an antifungal and notice unexplained weight gain, discuss it with your doctor. They may recommend monitoring liver enzymes or suggest dietary changes to support a healthy gut and metabolic rate while you complete your treatment.