Medications That Could Be Contributing to Your Weight Gain

43. Testosterone Replacement Therapy (TRT): The "Good" Weight Gain

When men begin Testosterone Replacement Therapy (TRT), they often experience an increase on the scale, but it's not always a bad thing. Unlike other medications that cause fat accumulation, TRT's primary effect is an increase in lean muscle mass and bone density. This increase in muscle is often accompanied by a boost in metabolism and energy, which can lead to a healthier body composition overall. However, some men may also notice some fluid retention, particularly in the beginning. It's important to differentiate between this muscle gain and unwanted fat. Focusing on a balanced diet and consistent resistance training can maximize the positive effects of TRT.

44. Calcium Channel Blockers: The Fluid Retention Factor

While a good option for lowering blood pressure, calcium channel blockers like amlodipine and nifedipine can cause a specific type of weight gain: fluid retention. These medications work by relaxing blood vessels, but they can cause swelling in the ankles, feet, and legs. This isn't fat, but it can lead to a frustrating increase on the scale. To combat this, patients can reduce their sodium intake, elevate their legs when resting, and engage in regular walking to improve circulation. If the fluid retention is significant, a doctor may adjust the dosage or add a diuretic (a "water pill") to help the body flush out the excess fluid.