Medications That Could Be Contributing to Your Weight Gain

47. Finasteride: A Hormonal Side Effect

Medications like finasteride (Proscar, Propecia) are commonly prescribed for benign prostatic hyperplasia (BPH) and male pattern baldness. These drugs work by inhibiting a hormonal enzyme, which can lead to a slight but noticeable weight gain. The mechanism involves hormonal shifts that can alter metabolism and body composition. For men taking these medications, a proactive approach is key. Implementing a consistent strength training routine and a diet rich in lean protein can help build muscle and counteract any metabolic slowdown, ensuring that while the medication does its job, you maintain a healthy weight and body composition.

48. Cyproheptadine: The Hunger Inducer

Often used off-label for migraine prevention or to stimulate appetite, cyproheptadine is a first-generation antihistamine with a significant side effect of weight gain. Unlike newer antihistamines, cyproheptadine is a potent serotonin antagonist, which directly impacts the brain's appetite center. This leads to an increased feeling of hunger and cravings, making it difficult to maintain a healthy diet. It's a powerful example of how a drug's secondary effects can be used for a different purpose, with an often-unwanted consequence. If you're taking this medication and noticing weight gain, discuss it with your doctor to explore alternative, weight-neutral treatments.