Medications That Could Be Contributing to Your Weight Gain
13. Statins: The Cholesterol-Lowering Culprit

Statins, including atorvastatin (Lipitor) and simvastatin (Zocor), are widely used to lower cholesterol levels and reduce the risk of heart disease. However, some people notice unexpected weight gain while on these medications, likely due to changes in metabolism and muscle fatigue, which can make exercise more challenging. Additionally, statins may slightly increase insulin resistance, which can lead to increased fat storage. While these effects are often mild, they can be frustrating for those actively working to maintain a healthy weight. What to Do: Focus on heart-healthy fats (like avocados, nuts, and olive oil), stay active with low-impact exercises to counteract fatigue, and consult your doctor about adjusting your dosage or exploring alternative cholesterol-lowering options if necessary.
14. NSAIDs: Pain Relief with Hidden Consequences

Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen (Advil), naproxen (Aleve), and diclofenac, are used for pain relief, inflammation, and arthritis. While not commonly linked to weight gain, long-term use may cause fluid retention and bloating. Additionally, NSAIDs can lead to gut inflammation, slow digestion, and cause water weight retention, especially when taken in high doses. People with chronic pain or arthritis may also move less, leading to gradual weight gain over time. What to Do: Drink plenty of water, limit sodium intake, and incorporate gentle movement (like stretching or walking) to prevent water retention. If pain management is affecting your activity levels, talk to your doctor about alternative pain relief options or physical therapy.