Medications That Could Be Contributing to Your Weight Gain

17. Thyroid Medications: A Complex Balance

People with hypothyroidism often take levothyroxine (Synthroid) or liothyronine (Cytomel) to regulate their thyroid hormone levels. While these medications are meant to support metabolism, some people experience weight gain due to incorrect dosing. An underactive thyroid can slow metabolism and cause fatigue, fluid retention, and difficulty losing weight—even while on medication. Sometimes, weight gain may persist due to improper hormone balance. What to Do: Work with your doctor to regularly monitor thyroid levels to ensure your medication is working effectively. Incorporate strength training and whole foods to support a stable metabolism.

18. Muscle Relaxants: Relaxation with a Trade-Off

Muscle relaxants such as cyclobenzaprine (Flexeril) and methocarbamol (Robaxin) are commonly prescribed for muscle spasms and chronic pain. However, these medications can cause drowsiness, slowed metabolism, and reduced activity levels, all of which may contribute to weight gain. Additionally, muscle relaxants may increase appetite and cause bloating, particularly when used long-term. What to Do: Try low-impact movement like stretching or swimming to counteract inactivity. If weight gain becomes a concern, discuss alternative pain management strategies with your doctor.