12 Science-Backed Ways to Make the Ultimate Immune-Boosting Holiday Cocktail (Yes, Really!)

5. Honey and Manuka: Soothing sweetness with a long history

Honey has a long culinary and cultural history as a soothing sweetener with antimicrobial reputation in traditional use. In cocktails, honey gives body and a rounded sweetness that pairs especially well with lemon, ginger, and bourbon. Make a honey-citrus toddy by mixing hot water, a spoonful of honey, a squeeze of lemon, and a shot of whiskey—this is more of a restorative sipper than a party punch, but it’s comforting on chilly evenings. Manuka honey is often marketed with stronger antimicrobial claims, but avoid medical promises; as a flavor choice, it’s richer and can stand up to bolder spirits. Use honey-based syrups to sweeten drinks without overly masking constructive ingredients like citrus or turmeric. Honey also dissolves well into warm mixes, making it a natural fit for mulled-cider style cocktails.

6. Pomegranate: Antioxidants and festive color

Pomegranate juice is rich in polyphenols and adds a luxuriously deep color to holiday cocktails. Use pomegranate juice as part of a spritz or mix it with a mineral water base and a lower-proof spirit for a refreshing, antioxidant-forward option. Pomegranate molasses brings tart concentration and works beautifully in spiced rum cocktails or with whiskey. Because juices add sugar, balance flavors with fresh citrus, a splash of club soda, or herbal bitters to keep the drink refreshing instead of cloying. When possible, choose 100% pomegranate juice or press fresh seeds for peak flavor. Enjoy pomegranate as a way to layer antioxidants into a festive drink without suggesting it’s a cure—think of it as a tasteful, nutrient-aware ingredient rather than a treatment.