11 Bizarre Twists Your Body Takes on the Lorazepram Rollercoaster

7. Respiratory Depression

Respiratory depression, characterized by slow or shallow breathing, is a serious potential complication of lorazepam use. This risk elevates when lorazepam is combined with other central nervous system depressants, such as opioids or alcohol. Elderly individuals and patients with existing respiratory conditions, like chronic obstructive pulmonary disease (COPD) or sleep apnea, are at heightened risk. Symptoms include difficulty breathing, blue-tinged lips or fingernails, and excessive drowsiness that progresses to unconsciousness. It is crucial for patients to inform their doctor if they have a history of breathing problems or if they use medications that also depress respiration. In hospital settings, staff may monitor oxygen levels or provide supplemental oxygen for patients taking lorazepam, especially if high doses are administered. If a patient outside of a hospital environment notices signs of respiratory distress—such as extreme fatigue or slowed breathing patterns—they should seek emergency medical care immediately. Prompt intervention, which may involve supportive breathing measures or reversal agents, can be life-saving in cases of severe respiratory depression.

8. Mood Or Behavior Changes

While lorazepam is primarily prescribed to reduce anxiety and induce sedation, some patients experience paradoxical effects such as increased agitation, irritability, or even aggression. These mood or behavior changes can manifest unexpectedly and may be more common in children, the elderly, or individuals with a history of mental health disorders. Patients might notice heightened anxiety rather than relief, and they could act out in uncharacteristic ways. Loved ones and caregivers should keep a close eye on any shifts in disposition, especially if it involves risk-taking behavior or hostility. Medical professionals typically evaluate whether these mood changes stem from lorazepam or from coexisting conditions, and they might recommend altering the dosage or switching to a different medication. If a patient exhibits intense mood swings or harmful thoughts, immediate psychiatric evaluation is warranted. In certain cases, combining lorazepam with other therapeutic methods—like counseling or cognitive-behavioral therapy—may help stabilize mood while still addressing the original reasons for taking the medication.