11 Bizarre Twists Your Body Takes on the Lorazepram Rollercoaster
9. Allergic Reactions

Though relatively rare, allergic reactions to lorazepam can occur and may manifest as hives, rashes, itching, or swelling—particularly in the face, lips, or throat. In severe situations, patients could experience difficulty breathing or anaphylaxis, which is a life-threatening condition requiring immediate emergency treatment. Individuals with known allergies to other benzodiazepines should exercise caution and consult thoroughly with their healthcare provider before starting lorazepam. Patients are encouraged to watch for any signs of unusual swelling or skin changes when they begin taking this medication, especially during the first few doses. If an allergic reaction is suspected, medical attention is crucial to prevent complications. Treatment may include antihistamines or steroids, and in extreme cases, epinephrine might be administered. After an allergic reaction, doctors typically re-evaluate the patient’s medication regimen, possibly switching to a non-benzodiazepine alternative or exploring other anxiety management strategies. Recognizing and treating allergic reactions promptly can prevent serious harm and guide safer future treatment options.
10. Loss of Coordination

Loss of coordination is one of the most frequently reported side effects of lorazepam use. This side effect is typically worse when larger doses of the medication are used, and patients who are elderly could be affected more severely. Patients have reported feeling unsteady on their feet, and this increases the risk of falls. In conjunction with unsteadiness, patients have also reported dizziness and weakness. Individuals who feel unsteady or dizzy while taking lorazepam should be especially careful to sit up slowly when getting up from a lying position, and it is equally important to take care when standing up from a sitting position. Throw rugs and other trip hazards should be removed from the patient's home, and it may be necessary for the patient to use a cane, walker, or another device to minimize the risk of falls. Any changes in coordination should be evaluated by the patient's physician to determine whether they stem from an underlying medical condition or whether they are just a side effect of the lorazepam.
