11 Common Medications Secretly Packing on the Pounds
9. Antiretrovirals: Managing HIV with Metabolic Challenges

Antiretroviral therapy (ART) is essential for managing HIV, transforming it from a fatal disease to a manageable chronic condition. However, some antiretroviral drugs, particularly older ones, have been linked to weight gain and changes in body fat distribution. These metabolic changes can increase the risk of cardiovascular diseases and diabetes. Patients on ART should be closely monitored for weight changes and metabolic complications. Healthcare providers should consider newer antiretroviral regimens with a more favorable metabolic profile and encourage lifestyle modifications to support overall health.
10. Antimigraine Medications: Headache Relief with Added Weight

Certain medications used to prevent migraines, such as amitriptyline and valproate, can contribute to weight gain. These drugs, while effective in reducing the frequency and severity of migraines, may alter appetite and metabolism. The challenge for migraine sufferers is to balance headache relief with maintaining a healthy weight. Patients should be informed about these potential side effects and work with healthcare providers to explore alternative treatments or adjust dosages. Lifestyle interventions, including regular physical activity and dietary modifications, can also play a crucial role in managing weight.
