11 Unexpected Benefits (and Risks) of Long-Term Antidepressant Use

4. Physical Health Impacts: Weight Changes and Metabolic Effects

Long-term use of antidepressants can significantly impact physical health, particularly in terms of weight and metabolism. Some antidepressants are associated with weight gain, which can increase the risk of developing metabolic syndrome, diabetes, and cardiovascular diseases. Conversely, other medications may lead to weight loss or appetite suppression. These physical changes can affect self-esteem and mental health, creating a complex interplay between physical and psychological well-being. Understanding these potential side effects is critical for patients and healthcare providers, as they can inform lifestyle modifications and additional treatments to mitigate adverse effects while maintaining the antidepressant's therapeutic benefits.