11 Unexpected Ways Your Medications Can Deplete Essential Vitamins

11. Metformin and Vitamin B12: The Diabetes Dilemma

Metformin, a cornerstone medication for Type 2 diabetes, is incredibly effective at lowering blood sugar. However, its long-term use is strongly associated with the depletion of Vitamin B12. Metformin can interfere with B12 absorption in the small intestine, leading to deficiencies that manifest as fatigue, nerve damage (neuropathy), memory problems, and even anemia. This is a critical concern for millions of patients relying on Metformin. Regular B12 level monitoring and, often, supplementation (especially via sublingual forms or injections) are essential for patients on this medication to prevent neurological complications and maintain overall vitality.