11 Unexpected Ways Your Medications Can Deplete Essential Vitamins
8. Proton Pump Inhibitors and Magnesium

Proton pump inhibitors (PPIs), used to treat gastroesophageal reflux disease (GERD), can significantly reduce the absorption of magnesium, an essential mineral involved in numerous biochemical reactions. Magnesium deficiency can lead to muscle cramps, fatigue, and cardiovascular issues. Long-term use of PPIs requires careful management of magnesium intake, either through dietary sources or supplements, to prevent deficiency and maintain overall health.