14 Nutrients That May Be Depleted by These Widely Used Medications

5. The Folate Paradox: Anticonvulsants and Neural Health

Folate (Vitamin B9) is crucial for cell division and DNA repair. Medications like methotrexate (for arthritis/cancer) and some anticonvulsants directly interfere with its action or deplete its levels. This can lead to fatigue, mouth sores, and even nerve issues. The ingenious solution often recommended by doctors is supplementation with the active form of folate, L-methylfolate (5-MTHF), which bypasses some of the metabolic blockades caused by these drugs, ensuring your cells get this vital nutrient.

6. Vitamin B12: The Hidden Cost of Metformin

Metformin, a diabetes workhorse, and long-term use of acid-blocking medications (PPIs, H2 blockers) can significantly impair Vitamin B12 absorption, leading to nerve tingling, fatigue, and cognitive fog. An ingenious tip for those on these medications: discuss sublingual (under-the-tongue) B12 supplements or B12 injections with your doctor. These methods bypass gut absorption issues, delivering this crucial nutrient directly into your system to protect your nerves and energy levels.