15 Unexpected Twists Your Body Takes With Diuretics
11. Frequent Urination

Frequent urination is a hallmark effect of diuretics, but for some patients, it can become bothersome. Needing to urinate multiple times throughout the day—or waking up several times at night—can disrupt daily routines and sleep. Doctors may suggest taking the medication earlier in the day to minimize nighttime trips. Maintaining a fluid diary can help track patterns, and in some cases, a timed voiding schedule can reduce urgency. If the issue affects quality of life, a dosage or medication change may be needed.