16 Things Your Doctor Didn't Tell You About Prednisone

5. Prednisone and Bone Health

One of the more concerning long-term effects of prednisone is its impact on bone health. Chronic use of prednisone can lead to osteoporosis, a condition characterized by weakened bones and an increased risk of fractures. This occurs because prednisone interferes with the balance of bone remodeling, reducing the formation of new bone while increasing bone resorption. Patients on long-term prednisone therapy are often advised to undergo regular bone density screenings and may be prescribed supplements or medications to help protect their bone health. Understanding the relationship between prednisone and bone health is essential for preventing complications and ensuring that patients receive comprehensive care that addresses both the benefits and risks of treatment.

6. The Impact of Prednisone on Sleep

Prednisone's effects on the body extend to sleep patterns, often leading to insomnia or disrupted sleep. This is primarily due to its stimulating effect on the central nervous system, which can interfere with the body's natural sleep-wake cycle. Patients may experience difficulty falling asleep, frequent awakenings during the night, or early morning awakenings. These sleep disturbances can exacerbate other symptoms, such as fatigue and mood changes, creating a cycle that can be challenging to break. Addressing sleep issues is an important aspect of managing prednisone therapy, and strategies such as adjusting the timing of doses, practicing good sleep hygiene, and, in some cases, using sleep aids can be beneficial in mitigating these effects.