Astonishing Ailments Prednisone Packs a Punch Against

13. Ulcerative Colitis

A woman in casual wear experiences abdominal discomfort while lying on a pink couch indoors. Photo Credit: Pexels @Polina Zimmerman

Ulcerative colitis is an inflammatory bowel disease that causes chronic inflammation and ulcers in the colon and rectum. Symptoms include abdominal pain, frequent diarrhea (sometimes with blood), fatigue, weight loss, and urgency to defecate. The severity of the disease varies from mild to debilitating, with periods of remission and flare-ups. While the exact cause is unknown, ulcerative colitis is believed to involve genetic, immune, and environmental factors. Diagnosis is confirmed through colonoscopy, stool tests, and blood tests. Treatment aims to control inflammation and prevent complications. Prednisone is commonly prescribed to manage moderate to severe flare-ups, rapidly reducing intestinal inflammation. However, long-term steroid use is avoided due to side effects, and patients are often transitioned to other medications like aminosalicylates, immunomodulators, or biologics for maintenance therapy. Dietary changes and stress management techniques can also play an essential role in managing the disease and improving a patient’s quality of life.

14. Temporal Arteritis

Close-up of a man holding his cheek, displaying a wide open mouth against a yellow background. Photo Credit: Pexels @Towfiqu barbhuiya

Temporal arteritis, also known as giant cell arteritis, is an inflammatory disease affecting the large blood vessels, particularly those in the head and neck. This condition is most commonly diagnosed in individuals over the age of 50 and is associated with symptoms such as severe headaches, scalp tenderness, jaw pain while chewing, and vision problems. If left untreated, it can lead to blindness or stroke. Diagnosis typically involves blood tests, a biopsy of the temporal artery, and imaging studies. Treatment must begin immediately to prevent complications, and prednisone is the first-line treatment to quickly reduce inflammation and minimize the risk of vision loss. Patients may need to take corticosteroids for several months or even years, with dosages gradually tapered down to minimize side effects. Regular follow-ups are necessary to monitor disease activity and adjust medication as needed. In some cases, additional immunosuppressive drugs may be prescribed for long-term management.

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