Unexpected Twists and Turns in the Gabapentin Journey

Lisette Marie

5. The Dark Side—Gabapentin and Suicidal Thoughts

Depression. Photo Credit: Dreamstime @Dreamz

A rare but serious gabapentin side effect is its impact on mental health. Some patients experience suicidal thoughts, extreme mood changes, and even paranoia. The FDA has issued warnings about this risk, urging patients to watch for changes in mood and behavior. While this effect is not common, it’s a critical consideration for anyone taking the drug—especially those with a history of depression or anxiety.

6. The Withdrawal Shock—Why Stopping Gabapentin Can Be Risky

Anxiety. Photo Credit: Envato @nuttapong_mohock

Gabapentin isn’t a controlled substance, but quitting suddenly can lead to serious withdrawal symptoms. Patients stopping gabapentin have reported insomnia, anxiety, nausea, sweating, and even seizures—even if they weren’t taking it for epilepsy. Tapering off slowly is crucial, especially for those taking it long-term or in high doses.

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5. The Dark Side—Gabapentin and Suicidal Thoughts

6. The Withdrawal Shock—Why Stopping Gabapentin Can Be Risky

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