Unexpected Twists and Turns in the Gabapentin Journey

9. Commonly Prescribed Alternatives

Gabapentin is often prescribed alongside opioids for pain relief, but the combination dramatically increases the risk of overdose. The FDA has issued a warning that gabapentin and opioids together can slow breathing and even cause death. Patients on both medications must be closely monitored.

10. Gabapentin and Weight Gain—An Unwelcome Surprise

While not everyone gains weight while taking gabapentin, many patients notice unexpected changes in their body composition. This drug has been linked to increased appetite, fluid retention, and metabolic changes, all of which can contribute to gradual or even rapid weight gain. Some individuals report cravings for carbohydrates and sugary foods, leading to a higher calorie intake without realizing it. Additionally, gabapentin may cause sluggishness and fatigue, making it harder to stay active, which can further contribute to weight gain over time.