Unexpected Twists Your Body Takes on the Prednisone Adventure
20. The Link Between Prednisone and Thinning Skin

Prednisone affects collagen production, leading to thinner, more fragile skin that bruises easily. Some patients notice stretch marks or slow-healing wounds, as the skin loses its ability to regenerate efficiently. Long-term users may experience more pronounced skin aging, making hydration and gentle skincare essential.
21. The Emotional and Physical Recovery After Stopping Prednisone

Even after tapering off prednisone, many patients report feeling "off" for weeks or even months. This is because the body needs time to rebalance cortisol levels and adjust to functioning without the drug. Some people experience fatigue, joint pain, mood swings, or lingering inflammation after stopping prednisone. Slowly rebuilding exercise, stress management, and proper nutrition can help smooth the transition.