Overview Of Bupropion (Wellbutrin)

Emily Fowler

Potential Medication Interactions

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This medication is associated with over four hundred potential medication interactions, including more than two hundred major drug interactions. Bupropion must be used with extreme caution in patients taking antiepileptic drugs. An antiepileptic drug called carbamazepine is believed to reduce the effectiveness of bupropion. Ritonavir, an HIV medicine, has been shown to reduce the body's concentration of bupropion by up to sixty-six percent.

Individuals who are currently withdrawing from benzodiazepines are at an increased risk of seizures if they use this medication as well. This includes diazepam and alprazolam. Thus, a different medication may be considered. Due to the risk of severe side effects, this medication should not be used within fourteen days of treatment with a monoamine oxidase inhibitor.

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Potential Medication Interactions

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