Common Side Effects Of Analgesics
Constipation

Constipation is a prevalent side effect in individuals using acetaminophen and opioid-based analgesics, primarily due to the concentrated opioid receptors in the digestive tract. Activation of these receptors leads to impaired gastric emptying, prolonged food transit time, decreased mucous secretions, and increased fluid reabsorption, resulting in dry and hard stool. Long-term analgesic use often necessitates additional medications to manage constipation effectively. Understanding the complex mechanisms contributing to constipation helps healthcare providers tailor interventions for individual patients.
Educating patients on the potential gastrointestinal effects of analgesics and implementing proactive measures, such as dietary modifications and prescribed medications, can enhance overall treatment outcomes. Monitoring and addressing constipation are integral aspects of comprehensive pain management.