Common Side Effects Of Analgesics
Fatigue

Fatigue, characterized by reduced energy levels and decreased efficiency, is a common side effect in individuals taking acetaminophen and analgesics containing opioids. While opioids suppress pain signals, they concurrently exert a suppressive effect on the central, peripheral, and autonomic nervous systems. This suppression impacts subconscious functions regulated by the autonomic nervous system, influencing an individual's alertness and energy levels. Fatigue may persist with continued medication use or gradually subside as the body adapts to the effects on the nervous system.
Recognizing the relationship between analgesic use and fatigue is crucial for healthcare providers when managing pain in their patients. Open communication and monitoring help tailor treatment plans to minimize fatigue-related disruptions to daily functioning.