Common Side Effects Of Analgesics
Rash Or Itching

The development of a rash or itching is a potential side effect for individuals using acetaminophen and opioid-based analgesics. While allergic reactions are rare with opioids, pseudoallergic or hypersensitivity reactions are more common. These reactions may occur on the first use of the drug, with itching sensations triggered by opioid receptors in the brain and spinal cord. Understanding the distinction between true allergies and hypersensitivity reactions is essential for accurate diagnosis and appropriate management.
Patient education on potential skin-related side effects, vigilant monitoring for early signs of reactions, and collaboration with healthcare providers enhance the safety and efficacy of analgesic use. Adjustments to the analgesic regimen may be considered based on the individual's response and tolerance.