Guide To Baclofen
Potential Medication Interactions

Baclofen has twenty-four major interactions and over three hundred moderate interactions. Serious side effects may occur if this medicine is taken with other muscle relaxers or with opioids, including codeine. Moderate drug interactions could develop if this medication is used with levomethadyl or buprenorphine. Increased drowsiness might occur in patients who use this medicine with benzodiazepines. One example of this is triazolam.
To reduce the risk of interactions, patients should let all of their doctors know about all of the medicines they use. This list needs to include prescriptions, over-the-counter drugs, vitamins, minerals, and nutritional supplements. The patient's pharmacist should check for potential interactions before dispensing this medication.