Guide To The Most Common Antidepressants

Atypical Antidepressants

Atypical antidepressants include any antidepressants that work differently than the previously mentioned ones. Many types of atypical antidepressants work by increasing levels of dopamine and norepinephrine in the brain. They are often considered in cases of treatment-resistant depression that has not responded to other antidepressants. In addition, doctors may choose to prescribe atypical antidepressants for patients trying to quit smoking, as the drugs have been shown to reduce nicotine cravings. Bupropion is one of the most common atypical antidepressants in use today.

Patients who take these medications should be aware of potential side effects such as dry mouth, dizziness, constipation, diarrhea, and weight gain. Esketamine, a new nasal spray intended for use in patients with treatment-resistant depression, must be administered by a psychiatrist or a primary care doctor. Bupropion should not be used by patients who have a history of seizures or eating disorders. Patients should check in regularly with their healthcare team during treatment with atypical antidepressants. If troublesome side effects occur, it may be possible to switch to another medication in the same drug category.

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Noradrenaline And Specific Serotonergic Antidepressants

Some patients may take noradrenaline and specific serotonergic antidepressants (NASSAs). This type is common for individuals who cannot take SSRIs. They are also used to treat some personality disorders and anxiety in addition to depression. Ultimately, the effect of this medication is to enhance the transmission of adrenaline and serotonin in the brain, specifically when it comes to mood regulation.

Information surrounding NASSAs suggests they carry fewer side effects than SSRIs.However, side effects can happen, and typically include drowsiness, dry mouth, weight gain, dizziness, constipation, and blurry vision. Two common NASSAs are mirtazapine and mianserin. The former is quite sedating, and is particularly helpful for patients with insomnia or high anxiety as part of their condition.

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