Guide To Dapsone (Aczone)

Potential Medication Interactions

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Patients should inform their doctor about all of the prescriptions and over-the-counter medicines they use before taking dapsone. They should let them know about any vitamins, minerals, or herbal supplements as well. This information should help doctors avoid potential medication interactions. Patients should ask their pharmacist to check for potential medication interactions before dispensing the medicine.

Dapsone is known to interact with nitrofurantoin and primaquine. It also interacts with pyrimethamine and other folic acid antagonists. If patients take dapsone with saquinavir, it could change how it is removed from the body. This may alter the effectiveness of dapsone as well. The oral form of dapsone can make the oral typhoid vaccination less effective. Thus, individuals who are getting any vaccination should let their doctor know that they are taking it.

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