Guide To Dexamethasone
Potential Medication Interactions

Dexamethasone has potential medication interactions with more than 650 drugs, with over one hundred of these being major ones. Thus, patients should let their doctor know about all prescription medicines, over-the-counter drugs, and supplements they use. Pharmacists should check for potential interactions before dispensing this medication. Patients should also make sure that their doctor always has an updated list of their current medicines. This helps them reduce the risk of potential interactions.
This drug interacts with aldesleukin and other cancer medicines. Examples of these include rilpivirine, praziquantel, dasatinib, and lapatinib. Ideally, patients should not take it with the first two. Additionally, this medication reduces the effectiveness of both lapatinib and dasatinib. If patients must take it with either one, they may need to have their doses adjusted. They may also need to be monitored more closely. Dexamethasone interacts with antiplatelets, anticoagulants, and certain nonsteroidal anti-inflammatory drugs, including ibuprofen. Individuals who take a daily Aspirin should ask their doctor if they need to discontinue it while taking dexamethasone.