Guide To The Side Effects Of Ibuprofen

Diarrhea Or Constipation

Ibuprofen and other nonsteroidal anti-inflammatory drugs have been known to sometimes result in diarrhea and constipation. Constipation is reported as a more common side effect to ibuprofen than diarrhea is, although both can occur. Ibuprofen eats away at the mucosal layer that protects the linings of the intestines and stomach. The mucus production in these organs is imperative for the proper lubrication and movement of food through the gastrointestinal tract. Less mucus means less lubrication, and less muscle movement to propel the food along at a reasonable pace. Food stays in the digestive tract for longer than it typically would, allowing the intestines to absorb more fluid from it before it exits the body. Increased fluid reabsorption in the stool means the stools become dry and hard, causing the individual to feel constipated. Inflammation in the small and large intestinal linings can also cause diarrhea if the ability of the intestine to absorb certain nutrient components from the food has become impaired. Irritation of the intestinal linings can also overstimulate the muscles that help move food along the intestines, causing it to move too quickly and results in diarrhea.

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Decrease In Urine Output

Patients who take ibuprofen could experience a decrease in urine output. This side effect is relatively common, and it might occur in conjunction with a decrease in the concentration of urine as well. These decreases are most likely to develop in female patients over sixty years old, and individuals who take ibuprofen and acetaminophen at the same time are also at an increased risk of decreases in urinary output and concentration. Changes in urinary output are typically reported within the first month of ibuprofen use. Patients who take ibuprofen for a longer period are less likely to report urinary issues. Individuals who have a medical condition known as patent ductus arteriosus have an elevated risk of urinary side effects while on ibuprofen. Since changes in urination could be indicative of an underlying health issue, patients who notice this side effect should report it to their physician right away.

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