Guide To Benzoyl Peroxide
Potential Medication Interactions

Patients should talk to their doctor about all prescription medications, over-the-counter drugs, and supplements they use. Doctors can determine the safest and most effective combination of medicines for the patient's needs. Benzoyl peroxide may interact with other topical medications used to treat skin conditions. It interacts with the topical forms of dapsone, adapalene, bexarotene, tretinoin, and trifarotene. It also interacts with isotretinoin. This is an oral medication used to treat severe acne.
Patients who use these medicines should check with a doctor about if they can safely use benzoyl peroxide. When these medicines are combined, there is an increased risk of skin dryness and other side effects. It may be necessary to adjust the combination of medications or doses to minimize side effects.