Overview Of Antidepressants

Medication Interactions

SSRIs should not be taken with tricyclic antidepressants, monoamine oxidase inhibitors, or other medicines that increase serotonin levels in the brain. Taking them together could lead to a dangerous condition known as serotonin syndrome. In addition, patients should avoid using anti-inflammatories during treatment with SSRIs if at all possible. The use of these medications together is associated with an increased risk of gastrointestinal bleeding. Tricyclic antidepressants are known to interact with many medications as well. Examples include clonidine, cimetidine, and amitriptyline.

Patients should inform their doctor of all prescription and over-the-counter medicines, herbal supplements, and natural remedies that they are using before any antidepressant is prescribed. Pharmacists will also check for potential drug interactions before dispensing the prescription.

Switching Antidepressants

Many patients do not experience perfect results from the first antidepressant they try. In many cases, their doctor will adjust their dose first. This can help many patients, since some individuals will need a higher dose of the same medication than others. However, some patients may need to try more than one antidepressant before finding the one that works for them. Switching antidepressants is not a cause for concern, though it must be taken seriously.

First, patients should never stop taking their current medication before talking to their doctor. If it is an emergency, a phone call will be enough. In other cases, they should book an appointment and discuss it then. Doctors will be able to not only wean patients off their current antidepressant, but also switch them to one that they believe will be an appropriate alternative. Their instructions will help prevent side effects, withdrawal, and other issues. Overall, patients need to listen to their doctor and switch antidepressants under their direction.