Overview Of Losartan

Potential Medication Interactions

Patients should let their doctor know about all prescription medicines, over-the-counter drugs, and nutritional supplements they use before taking losartan. This will reduce their risk of potential medication interactions. Pharmacists should also check for any interactions before dispensing this medication.

Patients who take it with ACE inhibitors, valsartan, or other angiotensin receptor blockers are at a higher risk of low blood pressure, kidney damage, and high potassium. Nonsteroidal anti-inflammatories, such as naproxen and ibuprofen, should not be taken with this medication. Doing so could reduce the effectiveness of losartan. It may also increase the risk of kidney damage. Losartan increases lithium in the body. Patients who take lithium may need to have their dose reduced when taking losartan. Taking losartan with diuretics could increase a patient's risk of low blood pressure. Examples of diuretics that cause this include furosemide and spironolactone. Rifampin, a medicine used to treat tuberculosis, could make losartan less effective.