Side Effects Of Antidepressants

Blurred Vision

Blurred vision is most likely to occur as a side effect of tricyclic antidepressants, including amitriptyline, desipramine, and doxepin. These medications work by blocking the brain's receptors for a neurotransmitter called acetylcholine. As a result, tear production ceases, and the eyes become dry. Patients with blurred vision often describe it as a lack of visual clarity or sharpness, and it can occur in conjunction with sensitivity to light, a sensation of grit in the eyes, eye redness or itching, and a stinging feeling in the eyes. For most individuals, blurred vision resolves on its own within a few weeks of starting treatment with tricyclic antidepressants. Some patients may have difficulty driving, reading, or performing other daily tasks as a result of this change in vision, and it is important to have a comprehensive eye examination to rule out other causes. Patients should also mention this symptom to their primary care provider. Using a humidifier, artificial tears, and lubricating ointments could help in managing this side effect.

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Irritability

Irritability is a common side effect associated with many different types of antidepressants. Patients experiencing irritability may find minor issues tend to make them very annoyed or upset, and this side effect could lead to communication problems with family, friends, and co-workers. Over time, irritability might even cause tension and conflicts in relationships at home, school, and work. Some individuals may have anger, agitation, and mood swings in addition to irritability. While this side effect could be mild for certain patients, others might have extreme irritability. Generally, irritability as a side effect suggests the patient's antidepressant is not working for them. Patients and their family members should discuss this side effect with the prescribing physician. If irritability continues for a prolonged period or has a significant impact on the patient's relationships, it may be appropriate to consider trying other types of antidepressants. Patients might want to speak with a mental health professional about ways to manage irritability too.

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