Common Causes & Risk Factors Of Peptic Ulcer Disease

Medications

Certain medications can also cause peptic ulcer disease to develop, especially if a patient frequently uses acetylsalicylic acid, ibuprofen, naproxen sodium, ketoprofen, and other nonsteroidal anti-inflammatory medications. However, they do not include acetaminophen. The risk for this type of behavior increases significantly in women over the age of sixty, making them some of the most susceptible individuals to developing peptic ulcer disease. Older individuals who also take anti-inflammatory medications for osteoarthritis are also highly likely to develop this condition as well.

Nonsteroidal anti-inflammatory medications can irritate or inflame the lining of the stomach as well as the small intestine, possibly leading to peptic ulcer disease. Other medications, especially when combined with nonsteroidal anti-inflammatory medications, can increase the risk of developing ulcers. These medications include steroids, anticoagulants, selective serotonin reuptake inhibitors (SSRIs), alendronate, and risedronate.