Guide To The Side Effects Of Naproxen

Naproxen is a nonsteroidal anti-inflammatory medication commonly utilized to alleviate swelling, inflammation, joint pain, muscle aches, and stiffness. Naproxen may be used to treat other forms of mild to moderate pain in an affected individual, such as what occurs in bursitis, menstrual cramps, acute gout, ankylosing spondylitis, and tendonitis. This nonsteroidal anti-inflammatory drug works through a mechanism that involves decreasing certain hormones responsible for pain signals and inflammatory responses by the immune system. Naproxen comes in numerous different forms, including enteric-coated tablets, liquid suspension, extended-release tablets, liquid-filled capsules, and standard tablets. Naproxen has proven to be a successful medication for the treatment of muscle, joint, and other types of acute pain. However, it can produce adverse side effects in some individuals.

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Indigestion And Heartburn

Indigestion and heartburn tend to occur with the use of naproxen because this medication produces topical irritation to the epithelium or specialized linings of the esophagus, stomach, and intestines. Naproxen has also shown to cause an individual's mucosal barrier properties in the digestive tract to become impaired, leaving the underlying tissues more vulnerable to inflammation and damage. Gastric prostaglandin synthesis is a process that includes stimulation of bicarbonate and mucus secretions, inhibition of the secretion of acid, and adaptation of mucosal blood flow. Naproxen is known to stop the synthesis of prostaglandins in the digestive tract, removing a primary defensive mechanism the underlying tissues use for protection against dangerous agents. Naproxen also impairs the ability of the gastrointestinal tissues to repair themselves once the damage has been done. Indigestion and heartburn occur when damage occurs to the esophagus and stomach tissues due to the effects naproxen has on the defense mechanisms of these tissues.

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Stomach Pain

Stomach pain typically occurs in individuals who take naproxen regularly for extended periods. Naproxen has corrosive effects on the mucosal layer of the digestive tissues in individuals who take it in this way. An individual may develop ulcers in the esophagus or stomach when the tissues underneath the stomach's mucosal layer become damaged, and they continue to take naproxen regularly. The tissues of the stomach and esophagus contain a significant number of sensory nerves throughout that send pain signals to the brain when they are cellular damage occurs. Stomach pain as a side effect of naproxen is more likely to occur in individuals who have had prior conditions that have caused damage to the tissues in their esophagus, stomach, and intestines. The stomach pain from naproxen has been described as a burning or piercing pain that worsens upon the consumption of certain types of food that stimulate the production of stomach acid.

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